Between 10 and 50 percent of patients who receive an allogeneic transplant experience a side effect known as graft versus host disease (GvHD). GvHD may be acute (developing within the first 100 days) or chronic (developing beyond 100 days). 

The “graft” refers to the transplanted haemopoietic stem cells; the “host” refers to the patient. Thus, graft versus host disease refers to a condition in which the donor’s immune cells attack some of your organs. GvHD is the biggest single threat, other than the underlying disease, to the success of a bone marrow transplant.

Treatments are given to help prevent graft versus host disease, and generally include immunosuppressive medications, antibiotics, and sometimes steroids. If GvHD develops, additional treatment with high-dose steroids may lessen its severity. Symptoms can include skin rash, diarrhoea, liver damage, or other problems, depending upon the organ that is affected.

If a patient has never had GvHD then the risk of ever developing it lessens with time.  However if a patient has had GvHD once then they are at more risk of developing it again

Here is a leaflet on GvHD produced by the Royal College of Nursing

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